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Theoharis C. Theoharides, BA, MS, MPhil, PhD, MD, FAAAAI

Director, Center of Excellence for Neuroinflammation Research, Nova Southeastern University

Professor, Institute for Neuro-Immune Medicine


Dr. Theoharis C. Theoharides joined Nova Southeastern University (NSU) on July 1, 2022 as Professor at the Institute of Neuro-Immune Medicine, and Director of a new Center of Excellence on Neuroinflammation Research at the Clearwater campus. He has been Professor of Pharmacology and Internal Medicine and Director of Molecular Immunopharmacology & Drug Discovery, Tufts School of Medicine (1983-2022) and will remain as Adjunct Professor there.

Dr. Theoharides received his Bachelor of Art, Master of Science, Master of Philosophy, Doctor of Philosophy, and Doctor of Medicine from Yale University and was awarded the Winternitz Price in Pathology. He trained in internal medicine at New England Medical Center and received the Oliver Smith Award recognizing excellence, compassion and service.” He was awarded the Tufts Distinguished Faculty Recognition and Excellence in Teaching Awards multiple times, as well as the Alumni Excellence in Service Award. He also received a Certificate in Global Leadership from the Tufts Fletcher School of Law and Diplomacy and a Fellowship at the Harvard Kennedy School of Government. He first showed that the unique tissue immune cells, mast cells, play a key role in the pathogenesis of in autism spectrum disorder, as well as in other conditions that involve neuroinflammation such as chronic fatigue syndrome and Long-COVID syndrome.

Dr. Theoharides has over 486 publications with 46,491 citations placing him in the world’s top 2% of most cited authors and he is the top-rated expert on mast cells by Expertscape. He has received 37 patents and trademarks. He was inducted into the Alpha Omega Alpha National Medical Honor Society, the Rare Diseases Hall of Fame and the World Academy of Sciences. He also received the 2018 Who Is Who Lifetime Achievement Award and the Distinguished Humanitarian Award. Dr. Theoharides has also helped develop some unique supplements containing flavonoids (

Visit Dr. Theoharides' personal website, Mast Cell Master


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Theoharides (PI) 1/1/21-12/31/2023
Neuroimmune priming of human mast cells

Theoharides (PI) 1/1/19-8/30/2021
Effect of IL-38 on human microglia activation

Solve ME/CFS Initiative 2018 Ramsay Award
Theoharides (PI) 11/1/18-12/31/2019
Role of extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome



  • Neurohormonal markers in chronic rhinosinusitis
  • Compton RA, Lonergan AR, Tsillioni I, Conti P, Ronconi G, Lauritano D, Rebeiz EE, Theoharides TC. J Biol Regul Homeost Agents. 2021 May-Jun;35(3):901-908. doi: 10.23812/21-35-3-E2. PMID: 34231347.
  • Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference
  • Gotlib J, George TI, Carter MC, Austen KF, Bochner B, Dwyer DF, Lyons JJ, Hamilton MJ, Butterfield J, Bonadonna P, Weiler C, Galli SJ, Schwartz LB, Elberink HO, Maitland A, Theoharides T, Ustun C, Horny HP, Orfao A, Deininger M, Radia D, Jawhar M, Kluin-Nelemans H, Metcalfe DD, Arock M, Sperr WR, Valent P, Castells M, Akin C. J Allergy Clin Immunol. 2021 Jun;147(6):2043-2052. doi: 10.1016/j.jaci.2021.03.008. Epub 2021 Mar 11. PMID: 33745886.


Complete List of Dr. Theoharides' published work.

  • My mystery symptoms and mast cells



  • Dr Theoharides speaks at the 9-2023 NIH workshop on Neurologic Aspects of Long-COVID On SARS-CoV-2 spike protein, neuroinflammation and brain fog.


  • The Role of Mast Cells & Histamine in Interstitial Cystitis


  • IIMEC13 Anne Örtegren Memorial Lecture Professor Theoharis C Theoharides


  • Dr. Theoharides Sensitive Children


  • Live Webinar-Autism Research Coalition


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