NSU HPD Catalog 2021-2022

College of Pharmacy—Ph.D. Program 229 PHRP 7114—Molecular and Cellular Pharmacodynamics This course is a study of the considerations in operating and regulating cellular processes by manipulating receptors for therapeutic advantage through coupled signaling pathways. Recent developments in this technique as it applies to the treatment of disease will be presented. (48-0-3) PHRP 7203—Social Measurement and Techniques This course introduces students to the concepts of advanced measurement theory and methods used in research. It acquaints students with cutting-edge models in measurement theory and methods, as well as with the application of computer software used to implement those methodologies. After completing the course, students should be prepared to begin working on advanced applications of measurement in the sociobehavioral sciences. (48-0-3) PHRP 7204—Research Techniques and Instrumentation This course will augment the student’s rotation experiences with a broader view of state-of-the-art technologies and instruments used in pharmaceutical sciences research. It will allow the student to read the literature with greater understanding as methodological terminology begins to have more meaning. It is meant to be a broad survey of technologies, not provide a deep background in any specific technology. (48-0-3) PHRP 7205—Advanced Quantitative Methods This course exposes students to selected advanced empirical methods useful in social, behavioral, economic, and administrative research and provides them with hands-on experience in conducting empirical research. Within this context, this course covers a variety of topics including linear programming, network models, utility and game theory, panel data methods, instrumental variables methods, and propensity score matching approaches. The course will be presented in an application context. Examples from social, behavioral, economic, and administrative studies will be used to illustrate key ideas and methods. Prerequisites: HPH 7300 and HPH 7310 (48-0-3) PHRP 7209—Pharmacoeconomics This course provides an overview of pharmacoeconomics and some of the health outcome measurements that apply to health/pharmacy-related disciplines. The course is designed to focus on methodological principles of pharmacoeconomics analyses and the strengths and weaknesses of specific methods. Practical examples for successful implementation of these concepts are discussed. (48-0-3) PHRP 7211—Theories of Health-Seeking Behavior This course covers social and behavioral theories related to medication use, health services utilization, provider patient communication, and other health-seeking behaviors. Students will examine and apply select health behavior theories at the individual, interpersonal, and community level. They will examine research conducted using the theories, with emphasis in the pharmacy field. Students are expected to apply theories in defining research questions, in research design, and in data analysis. (48-0-3) PHRP 7220—Advanced Pharmacogenomics and Molecular Medicine This course is designed to educate students with an in-depth knowledge and understanding of the cellular and molecular bases that have evolved as the basis of human diseases. The course offers the contemporary molecular biological concepts to apply toward understanding molecular bases of individual variation, its application to drug response, and possible new interventions. Students will be able to understand and apply the knowledge of modern molecular biological techniques for diagnostics and detection of infection; gene defects; fingerprinting, transgenesis, biopharming, and immunotherapies; and the ever-developing field of gene therapy and regenerative medicine. (48-0-3) PHRP 7221—Advanced Graduate Research This research course is design to provide guidance to students through the complete research process, from formulation of a topic to data collection and analysis to completion of a final report. Students are encouraged to present research findings at appropriate professional conferences. (80-0-5) PHRP 7222—Applied Pharmacology Students will use pharmacological principles to study the effects of therapeutic agents on the central nervous system, the endocrine system, the gastrointestinal system, blood, and blood-forming organs. The course will address the rationale for the use of therapeutic agents; their effects on cells, tissues, organ systems, and patients; the mechanisms underlying these effects; the therapeutic value of specific drug effects; the limitation of the use of the agents; and the adverse effects of drugs. (48-0-3) PHRP 7226—Journal Club This course provides graduate students with an opportunity to critically read, interpret, and present research literature. The audience will be fellowpeers, postdoctoral students and faculty members. Students will prepare and present high-quality written and oral critiques of peer-reviewed publications in the biomedical field. This course will help students stay abreast of current knowledge in their, as well as their colleagues, fields of research; develop presentation skills; and promote interdisciplinary interactions. (16-0-1) PHRP 7229—Product Development and Industrial Pharmacy This course provides the student with the essential information about the various stages of the new drug approval process and drug development, including pre-formulation, comparison studies, suitability of pharmaceutical excipients, and formulation. Additionally, this course provides the student with the principles of pharmaceutical processing, such as filtration,