NSU HPD Catalog 2021-2022

228 College of Pharmacy—Ph.D. Program PHRP 7004—Advanced Physical Pharmacy This course presents application of underlying physical principles to formulate and develop various pharmaceutical products. It describes physical principles in both solid and nonsolid states. Students will learn howbasic physical principles are applied in development of current and novel pharmaceutical solids, semi-solids, and homogeneous and heterogeneous systems. Moreover, the course describes the importance, properties, and application of different polymer systems, new drug carriers, and rheology modifiers in developing current and novel dosage forms. Drug stability and solubility and approaches to enhance the solubility of poorly soluble drugs will also be discussed. (48-0-3) PHRP 7006—Advanced Pharmacology This course will apply the principles of organic chemistry, biochemistry, physiology, and pathophysiology to understand drug actions at the receptor, cellular, and systems levels under physiological and pathological conditions. Special emphasis will be placed on students’ understanding of determinants of drug absorption, distribution, physiological receptors, drugreceptor interaction, drug metabolism, and elimination. This course will also focus on the drugs that act on the autonomic nervous system, cardiovascular system, and blood components as well. The rationale for the use of these therapeutic agents; their effects on cells, tissues, organ systems, and patients; the mechanisms underlying these effects; the therapeutic value of specific drug effects; and the adverse effects of the drugs will be addressed as well. (64-0-4) PHRP 7012—Clinical Drug Development: Advanced Pharmacokinetics and Biopharmaceutics This course deals with the principles that explain the processes of absorption, distribution, and elimination of drugs. The advances in pharmacokinetic modeling, compartmental analysis, model-independent methods, single and multiple dosing, protein binding, metabolite kinetics, interspecies scaling to translate animal data to humans, effect of disease states, and data analysis using relevant software will be discussed, applying the principles of biopharmaceutics and pharmacokinetics to the design of controlled release and targeted drug delivery systems. Emphasis is on bioequivalence and bioavailability of traditional pharmaceutical dosage forms and novel drug delivery systems, including the assessment of biosimilars. (48-0-3) PHRP 7020—Experimental Statistics and Informatics This course provides an overview of the principles of experimental statistics and informatics that are relevant to the experimental design of studies, as well as interpretation and processing of the information garnered from these studies, in the biomedical sciences, but particularly in the area of molecular medicine and pharmacogenomics. (16-0-1) PHRP 7021—Population Health and Public Policy This highly interactive course introduces students to: (1) the fundamental concepts and frameworks used for the study of population health and public policy; (2) the financing and managing of health systems at the local and international levels; and (3) the formulation and analysis of public health policies. The course will emphasize the intersection of public health and the determinant of drug use and pharmacy-related policies. Students will analyze and critically evaluate existing health policies, public health actions, and reforms. Students are expected to contribute and participate in the discussion of current research, case studies, and policies. Student learning will be assessed through oral exams, written assignments, presentations, and an analytical paper. This course will provide skills for the conceptualization of research projects addressing current health issues related to pharmacy. (48-0-3) PHRP 7023—Pharmaceutical Marketing This course is intended to provide the graduate student with an in-depth understanding of the global development and marketing of pharmaceuticals with an emphasis on the U.S. system. (48-0-3) PHRP 7025—Pharmacy Management and Finance This course provides an overview of management theories, human resources, and financial management applied to pharmacy and health care institution operations. Elements of supervision, management, and leadership are discussed in an effort to help students develop the skills needed to operate a pharmacy effectively. Also covered are finance topics such as capital costs, profit analysis, cost structures, budgeting, payment for services rendered, and accounting. (48-0-3) PHRP 7030—Biostatistics This course introduces methods for presenting data in summary form, analyzing data, and designing experiments. It emphasizes the application of statistical ideas and methods to the analysis and interpretation of experiments and comparative data. Students will be able to assess a situation involving data analysis, state the null and alternative hypotheses proposed, decide on the correct statistical procedure to test the null hypothesis and the assumptions of the test used, calculate the statistic, assess its statistical significance, and interpret the data in light of the calculated results. (48-0-3) PHRP 7060—Pharmaceutical Sciences Research Design The purpose of this course is to provide an analysis of the study designs most commonly employed in experimental research with emphasis in basic and clinical pharmacological research. Completion of the course is expected to enable students to understand the considerations that go into selecting qualitative, quantitative, andmixedmethods of research design. The course prepares students to select themost appropriate design to better answer a specific research question, as well as to understand the strengths and limitations of such design. (16-0-1)