528 College of Dental Medicine—Postdoctoral Programs CVR 7310—Fundamentals of Statistical Inference This is the second course in the biostatistics sequence and is intended for consumers of statistics in the biological and medical fields, as well as researchers. It will concentrate on the more advanced methods of statistical analysis that are typical of biological and medical applications of statistics. For this course, the student will need to be familiar with basic statistics and statistical techniques as presented in CVR 7300. Students will be using the statistical program R to perform statistical processing; therefore, students must have basic skills in the use of R. CVR 7400—Clinical Research Design This course will provide students with an understanding of the basic methods and approaches used in health-related research. A major emphasis of the course will be on the conceptualization and design of research studies. The course will cover ethics, formulation of research questions, study design, reliability, validity, sampling, measurement, and interpretations of research findings. It will prepare students to critically evaluate published research articles, to abstract information and interpret findings appropriately from the published literature, and to design sound research studies. The course will be both theoretical and practical. Students will be challenged to apply the theoretical concepts presented in the classroom and in the readings to design studies to address health-related issues of their choice. CVR 7500 Information Science for Clinical Research This course introduces the student to the concept of a literature review as it relates to the development of a research proposal. Students will specify a research problem and provide an appropriate review of the literature. This literature review will identify and discuss related research that sets the proposed project within a conceptual and theoretical context. Students will learn to use reference sources (both electronic and hard copy) available in most public and academic libraries and/or via the Internet to locate and evaluate literature pertinent to clinical and basic vision science and basic research in related medical sciences. Use of evidence-based medicine as a research tool will be covered. Students will be expected to identify and effectively utilize all relevant information resources in their geographical area essential to the preparation of a thorough, high-quality literature review. CVR 7600—Introduction to Research Funding and Proposal Development This course enables the student to gain an in-depth understanding of the essential components of a well-written research proposal that addresses an identified scientific problem and the process for submitting the proposal to an agency/organization, requesting funding support to study the problem. Students will become familiar with a number of funding sources, including federal and state government and private foundations and corporations that support vision or dental research projects, and learn to use a variety of resources to target potential funding sources. They will become familiar with various grant-related terminology, as well as guidelines, rules, and regulations of awarding agencies, with particular focus on the National Institutes of Health (NIH) organization. Students will be expected to come prepared to explore and discuss potential research areas they would like to study and to focus on ideas about projects to address their interests. They will be able to demonstrate their understanding of the essential components of a well-written proposal, including the significance statement, objectives and hypotheses, experimental design and methods, and the budget through class handouts, virtual discussions, and appropriate class activities related to the required readings. CVR 7800—Ethical and Legal Issues in Human Subjects Research This course introduces the ethical and regulatory aspects involved in human subject research. Students will gain understanding of the history that has shaped the rules that today govern research with human subjects, as well as be introduced to issues that researchers in the 21st century face. Students will become familiar with U.S. regulations that govern human subject research and the protection systems that are created as a part of those regulations. Issues related to research with a variety of vulnerable populations will also be discussed. Students will be expected to come prepared to explore and discuss the variety of critical issues researchers face when they hope to conduct human subject research. They will be able to demonstrate an understanding of the key elements of informed consent documents, including statements required by U.S. regulations. Class activities related to the readings and CITI modules will permit students to gain an understanding of these topics while also completing the NSU required CITI program. CVR 8220—Epidemiology This course provides a study of the basic principles of epidemiology, with emphasis on the application of epidemiology to clinical practice.
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