NSU HPD Catalog 2021-2022

College of Pharmacy—Ph.D. Program 231 PHRE 7213—Epidemiology of Drug Use, Abuse, and Misuse This course is designed to introduce doctoral students to the epidemiology of drug use, misuse, and abuse. The course focuses on drug use, misuse, and abuse as social phenomena and deals with the history of drug use and regulatory attempts in America; pharmacology and use patterns related to specific drugs; use, abuse, and misuse as medical, psychological, and social concepts; drug importation, manufacture, and distribution (including both the legal and illegal drug industries); perspectives on the etiology of drug use/abuse; drug abuse prevention and educational programs; and approaches to drug abuse treatment. (48-0-3) PHRE 7216—Pharmaceutical Polymers This course presents basic concepts and properties of polymers as related to formulation, development, and design of pharmaceutical dosage forms and products. It describes how basic principles of polymers—structural, physical, chemical, and mechanical properties—can be utilized in modifying and developing current and novel pharmaceutical products. Moreover, the course highlights important areas of polymer applications in controlled drug delivery, targeted drug delivery, tissue engineering, nanotechnology, and medical devices. (48-0-3) PHRE 7223—Drugs of Abuse This course covers types of substances abused, methods and routes of administration, the pertinent toxicokinetics, the pharmacological/toxicological mechanisms, and the clinical manifestations of drug abuse. Treatment of intoxication and withdrawal, societal impact of drug abuse, legal implications, and current trends of substance abusewill also be discussed. (48-0-3) PHRE 7252—Fundamentals of Pharmacognosy This course exposes graduate students to the field of pharmacognosy, with an emphasis on medicinal products derived from plants and other natural sources. The major classes of medicinally active natural products, their origin (nomenclature + taxonomy), structure, biosynthesis, andmode of action will be covered. The naturally derived constituents and their therapeutic efficacy will be discussed. Students will be required to develop a monograph for a bioactive plant or marine species, including a comprehensive summary of the peer-reviewed research available regarding its pharmacological profile. (48-0-3) PHRE 7340—Role of Pharmacy in Adolescent Health In this course, students will analyze different health situations that youth face during adolescence, from risky behaviors to chronic illnesses. It is an interactive course in which students will have the opportunity to explore, in depth, issues regarding adolescent health from human development, ecological, and cultural perspectives. The students will explore how pharmacists can contribute to the promotion or maintenance of adolescent health, the prevention of disease, and the management of chronic diseases. Students will be expected to prepare a literature review and design health promotion and education strategies on an issue of their choice. (48-0-3) PHRE 7350—Contemporary Issues in Pharmacy This course is designed to explore a broad spectrum of contemporary issues related to pharmacy practice, pharmaceutical industry, third-party payment, and health policy. It aims to increase student awareness and understanding of the change in pharmacy practices and their impacts to the U.S. health care system. (48-0-3) PHRE 7411—Current Topics in Pharmacy Practice Topics on current issues, procedures, and policies related to pharmacy practice are discussed. Topics can vary from semester to semester. (48-0-3) PHRE 7431—Oncologic Treatments and Pharmacogenomics This hybrid course introduces the basic molecular concepts of cancer and pharmacogenomics in the context of cancer treatment. It presents the current methodologies used in cutting-edge oncology for the treatment of two of the most common types of cancer: breast and colon. The standard-ofcare combinatorial regimens will be presented, as well as the treatment scenarios that are applied to advanced-stage and recurrent disease. Drugs that have increased patient tolerance to these genotoxic regimens will also be discussed. Finally, the application of next-generation sequencing of tumor DNA or RNA to determine which of the more than 300 druggable mutations exist in these tumors will be discussed, primarily in the cancerrecurrence setting. Prognostic tests based on RNA expression from tumors will be covered. Discussion of the rationale for insurance coverage of pharmacogenomic variability will be covered as well. The impact of oncologic pharmacogenomics on future clinical trials will also be examined. (43-0-3) PHRE 7447—Regulatory Affairs This course provides an exposure to the important and critical area of drug regulatory matters. It describes the role of federal laws, regulations, and the structure and operation of the U.S. Food and Drug Administration. It also compares similar agencies in other countries. (43-0-3) PHRE 7515—Health Disparities and Chronic Diseases: The Role of the Pharmacist This course presents the main causes and pathways to health disparities in the United States. It focuses on chronic diseases, such as diabetes, cancer, and cardiovascular diseases. Emphasis is given to disparities associated with access to medication and pharmacy services and to adherence. Students learn about pharmacy-led interventions aimed at reducing health disparities. They are expected to use epidemiological data to study the disparities and to formulate recommendations to the pharmacy field. Students are assessed through hands-on structured assignments. (48-0-3)