NSU HPD Catalog 2021-2022

216 College of Pharmacy—M.S. in Pharmaceutical Sciences PHRM (Master’s Degree) and HPD Core Classes Note: Listed at the end of each entry are lecture hours, laboratory hours, and credit hours. HPH 7210—Bioethics: Principles of Life Science Research This course provides a structured approach for identifying, analyzing, and resolving ethical issues in medicine and the life sciences. Students analyze and discuss traditional philosophical theories regarding the nature of moral good. They will apply these theories to critical issues and selected case studies involving experiments with human subjects, organ transplantation, in vitro fertilization, the use of animals in research, the collection and publication of research data, conflicts of interest, and other topics of current concern. Students will explore the personal values, professional standards, and institutional guidelines that define the roles and responsibilities of the health care practitioner and researcher. (48-0-3) HPH 7610—Scientific Writing This course exposes students to, and provides practice in, various types of writing skills necessary for scientists and researchers, including research logs, internal reports, technical reports, abstracts, presentations and journal manuscripts, dissertation formats, and grant applications. Students are exposed to various search databases, style manuals, and publication outlets. (16-0-1) PHRM 5001—Health Economics This course will introduce students to the economic analysis of health care markets and the production of health. This course covers a variety of topics including the determinants of health; the supply of, and demand for, health care services; the impact of insurance on the demand for health care services; the role of government in health care markets; the market for pharmaceuticals; and the economic evaluation of health care programs. (48-0-3) PHRM 5030—Biostatistics This course introduces methods for presenting data in summary form, analyzing data, and designing experiments. It emphasizes the application of statistical ideas and methods to the analysis and interpretation of experiments and comparative data. Students will be able to assess a situation involving data analysis, state the null and alternative hypotheses proposed, decide on the correct statistical procedure to test the null hypothesis and the assumptions of the test used, calculate the statistic, assess its statistical significance, and interpret the data in light of the calculated results. (48-0-3) Master of Science (M.S.) in Pharmaceutical Sciences Course Descriptions PHRM 5004—Advanced Physical Pharmacy This course presents application of underlying physical principles to formulate and to develop various pharmaceutical products. It describes physical principles in both solid and nonsolid states. Students will learn howbasic physical principles are applied in development of current and novel pharmaceutical solids, semi-solids, homogeneous, and heterogeneous systems. This course describes the importance, properties, and applications of different polymer systems, new drug carriers, and rheologymodifiers in developing current and novel dosage forms. Drug stability and solubility and approaches to enhance the solubility of the poorly soluble drugs will also be discussed. (48-0-3) PHRM 5012—Clinical Drug Development: Advanced Pharmacokinetics and Biopharmaceutics This course deals with the principles that explain the processes of absorption, distribution, and elimination of drugs. The advances in pharmacokinetic modeling, compartmental analysis, model-independent methods, single and multiple dosing, protein binding, metabolite kinetics, interspecies scaling to translate animal data to humans, effect of disease states, and data analysis using relevant software will be discussed, as will applying the principles of biopharmaceutics and pharmacokinetics to the design of controlled release and targeted drug delivery systems. Emphasis is on bioequivalence and bioavailability of traditional pharmaceutical dosage forms and novel drug delivery systems including the assessment of biosimilars. (48-0-3) PHRM 5014—Molecular and Cellular Pharmacodynamics This course studies the considerations in operating and regulating cellular processes by manipulating receptors for therapeutic advantage through coupled signaling pathways. Recent developments in this technique, as it applies to the treatment of disease, will be presented. (48-0-3) PHRM 5020—Advanced Pharmacogenomics and Molecular Medicine This course is designed to educate students with an in-depth knowledge and understanding of the cellular and molecular bases that have evolved as the basis of human diseases. The course offers the contemporary molecular biological concepts to apply toward understanding molecular bases of individual variation, its application to drug response, and possible new interventions. Students will be able to understand and apply the knowledge of modern molecular biological techniques for diagnostics and detection of infection; gene defects; and fingerprinting; transgenesis; biopharming; immunotherapies; and the ever-developing field of gene therapy and regenerative medicine. (48-0-3)