HPD Research Day | February 16, 2018

60 Amanda Feldstein, Nova Southeastern University Cameron Lombardi, Nova Southeastern University Andrew Miller, Nova Southeastern University Mongseyla Touch, Nova Southeastern University Objective. Determine the interrater reliability between an experienced clinician and a Doctor of Physical Therapy Student (SDPT) when performing the Upper Limb Tension Test with median nerve bias (ULTT1). Background. The ULTT1 is a common orthopedic test performed in physical therapy clinics designed to assess the mobility of the median nerve, accompanying branches, and associated nerve roots (C5,C6,C7). The ULTT1 has been shown to be an effective diagnostic test for conditions such as cervical radiculopathy, and a positive test may have prescriptive value. The reliability of the ULTT1 has been demonstrated, however, there is a paucity of evidence regarding the ability of a student to perform these tests in a comparable manner to that of an experienced clinician. Methods. Twenty healthy participants (mean age 25-years) were recruited via convenience sampling. Following consent, a second-year SDPT investigator and a clinician with 18 years of clinical experience performed the ULTT1 on each subject. A separate examiner recorded elbow extension range of motion (ROM) at the terminal point of the test, which was used for the analysis. Results. The intraclass correlation coefficient was .78 suggesting good interrater reliability. The MDC 95 was 12°. Conclusion. The ULTT1 used in this study possessed good reliability when comparing to a SDPT to an experienced clinician, thus extensive clinical experience may not be necessary to accurately perform the test. The MDC 95 indicates that changes of 12° or greater are needed to exceed the threshold of error. Atrium – Poster 63 12:15-1:15 p.m. Decreased Vision as Presenting Sign of Progression of Meningioma Zoeanne Schinas, O.D., Assistant Professor, College of Optometry, Nova Southeastern University Alexandra M. Espejo, O.D., Assistant Professor, College of Optometry, Nova Southeastern University Introduction. Brain tumors can present with different symptomatology depending on the location and size of the lesion. Meningiomas account for about 34% of all primary brain tumors, they tend to grow slowly, and may be large in size by the time symptoms present. Symptoms may include headaches, diplopia, visual disturbances, nausea and tinnitus or hearing loss. Case Presentation. A 39 y/o female presented for a contact lens exam with complaints of decreased vision in the left eye for the past 3-6 months. Medical history was significant for a benign cavernous sinus meningioma on the left side diagnosed 3 years prior. No defect was noted on ocular motility or confrontation fields. However, a left afferent pupillary defect was noted and she was unable to appreciate the HRR color plates in the left eye. Best corrected DVA was 20/20 right eye, 20/25 left eye. Pallor of the optic nerve neuro-retinal rim was noted in the left eye only. Humphrey visual field testing revealed an incomplete left hemianopsia. Deviation from the expected. A mild visual complaint in a patient with a known meningioma prompted the patient to present for an eye examination prior to neurological consult. Discussion. Patients with meningiomas require routine ophthalmological and neurological evaluation including imaging studies. The patient was referred to her neurosurgeon and a neuro- ophthalmologist. MRI testing confirmed that the tumor increased in size and affected the prequiasmatic, intracanalicular, and distal intraorbital segment of the left optic nerve. Conclusion. An interdisciplinary approach is recommended for all patients with brain tumors and especially with meningiomas due to the likely presentation of ocular symptoms. Recommendations for ophthalmological baseline and follow up testing will be discussed. Grants. N/A Atrium – Poster 64 12:15-1:15 p.m. Regulation of Cellular Cobalamin Acquisition and Processing by Nrf2 and mTORC1 Downstream of Neurotrophic Factors Matthew S. Schrier, BS, Ph.D. student in Pharmacy, College of Pharmacy, Nova Southeastern University Yiting Zhang, Ph.D., Waters Corporation Malav S. Trivedi, Ph.D., Assistant Professor, College of Pharmacy, Nova Southeastern University Richard C. Deth, Ph.D., Professor, College of Pharmacy, Nova Southeastern University