HPD Research Day | February 16, 2018

46 approach their learning in a variety of ways as identified through the VARK assessment. Grants. The study was not funded by any party. Atrium – Poster 35 12:15-1:15 p.m. Health, Exercise, and Sexual Dysfunction: A Comparison of Men and Women Lia M. Jiannine, Ph.D., Assistant Professor, Dr. Pallavi Patel College of Health Care Sciences, Nova Southeastern University Background. Obesity and inactivity have led to an increasing number of individuals with sexual dysfunctions (43% of women; 31 of men). Small bouts of exercise can drastically improve sexual functioning. Thus, the present study is designed to examine the effects of physical fitness and self-concept on sexual functioning. Subjects and Methods. Fitness assessments and questionnaires were administered to 133 participants between the ages of 18 - 50. Physical fitness was assessed through body composition, cardiovascular endurance, muscular strength and muscular endurance. Self-concept was presented a total self-concept score and as six individual concepts of self. Sexual function was presented as both an aggregate score and five separate constructs of sexual functioning - fantasy/cognition, arousal, orgasm, behavior/experience, and drive/desire. Results. The results indicated that sexual behavior/experience was predicted by body fat percentage. In men, fantasy was related to total self-concept, sexual behavior/experience was related to likeability. In women, arousal was predicted by cardiovascular endurance. Total self-concept was related to both orgasm and sex drive/desire. Power and muscular strength were significantly related to number of sexual partners in women but not men. Conclusions. The present study adds to the growing body of evidence indicating a positive relationship between physical fitness and sexual health. Individuals with sexual dysfunctions, particularly women, who are not persuaded by the currently publicized benefits of physical activity, may be inclined to exercise to improve sexual functioning. Atrium – Poster 36 12:15-1:15 p.m. Minimizing Drug Extraction via Simultaneous Binding and Coagulation Yogesh N. Joshi, Ph.D., Ph.D. in Pharmacy Student, College of Pharmacy, Nova Southeastern University Riann Forbes, P1, College of Pharmacy, Nova Southeastern University Hamid Omidian, Ph.D., Professor, College of Pharmacy, Nova Southeastern University Objective. The study was conducted to determine the combined effect of binding and coagulation on drug extraction from a bentonite drug dispersion. Background. Previously, our laboratory has shown the successful use of bentonite clays to prevent drug extraction for IV abuse due to its complex formation with cationic drugs. In this work, we have enhanced the deterrence capacity of bentonite clays by coagulating the bentonite particles during the extraction process. Methods. A suspension was prepared by dispersing calcium bentonite (50, 75, and 100 mg) into a 10 mL solution (2.5 mg/mL) of dextromethorphan HBr (DMX), followed by an addition of 2 mg of PEO. Non-coagulated (control) samples were also prepared in a similar way without addition of PEO. All samples were analyzed by a UV- spectrophotometer at a wavelength of 271 nm. The % of drug entrapped was measured indirectly from the amount remaining in the filtrate. The amount of filtrate recoverable after dispersion of bentonite clay with and without coagulant was measured using a graduated cylinder. Results. A higher % of drug entrapped within coagulated clays in all dispersions compared to the control. As the amount of clay in the drug solution was increased, about 5-6.5 % increase in drug entrapment was observed. With the dispersed system, the recoverable filtrate volume was 9.4 mL whereas, the recoverable amount of filtrate was 8.6 mL for the coagulated system. Conclusion. The coagulation process affected the drug extraction process by causing around a 6% increase in drug entrapment and an 8% decrease in solvent recovery compared to a non-coagulated dispersed clay system.