2023 Division Of Research Annual Report

5 Genomics and Bioinformatics Core Introduction: NSU Core services include library construction and DNA sequencing for various genomics-level applications, including whole genome sequencing, exome sequencing, and transcriptomic profiling. The sequencing data can show specific genetic changes occurring within the genome of any organism. Transcriptome profiling reveals information on which genes in an organism are expressed in various tissues, allowing researchers to potentially model how organisms might adapt to changing environments. Application: Genomics and bioinformatics offer gateways to deeper understanding of how organisms, from corals to humans, function in healthy and diseased states. Technology: Principal equipment assets include Illumina’s NextSeq 500 platform and NanoString’s novel, digital, color-coded barcode technology on the nCounter analysis system. Support: Customized open-source and commercial software for data analysis are offered in conjunction. Cell Therapy Core Introduction: NSU’s Cell Therapy Core Facility provides expertise in processing of cells from primary tissues; expansion and differentiation of cells, including immune and stem cells; genetic modification of cells by viral vectors; and development of cell-based therapy products; among other services. Application: Quality assurance and control are essential to complying with NIH and FDA guidelines. Technology: NSU ensures a high-quality research environment by providing a HEPA filter, particle-controlled GLP-quality cell and tissue processing laboratory. Support: The lab boasts well-established SOP-driven processes and technical/lab support by experienced staff assistants. For a description of services, equipment, and pricing, or to request a quote, please visit nova.edu/research/core-facilities or reach out via email. Robin Krueger, Ph.D. Scientific Director for Research Facilities rkrueger1@nova.edu CONTACT NOVA S OU T H E AS T E RN UN I V E R S I T Y Scan to email.