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Mary Ann Fletcher, Ph.D.

Director, E.M. Papper Laboratory of Clinical Immunology, Institute for Neuro-Immune Medicine, Nova Southeastern University

Schemel Professor for Neuro Immune Medicine, Institute for Neuro-Immune Medicine, Nova Southeastern University

Professor Emeritus, University of Miami, School of Medicine

Mary Ann Fletcher, Ph.D., has over 40 years’ experience in laboratory immunology and as a senior scientist in interdisciplinary research. She has been the Director of the E.M. Papper Laboratory of Clinical Immunology for over 30 years and oversaw its recent relocation from the University of Miami to NSU. Along with being a laboratory director, Dr. Fletcher has been an Assistant Professor in Medicine and Immunology, and is currently the Institute’s first Schemel Professor for Neuro-Immune Medicine.

Dr. Fletcher has over 260 published articles in peer reviewed journals and book chapters. Her particular research focus is on the identification of clinically useful biomarkers in complex multi symptom illnesses such as HIV, ME/CFS and GWI.

Her research has been funded by the National Institute of Health, the Veterans Affair, and the Department of Defense. Dr. Fletcher also holds 2 U.S. patents for developing diagnostic tests related to infectious mononucleosis.

In addition to her current role as a CLIA certified Clinical Laboratory Director and Endowed Professor, Dr. Fletcher is on the manuscript review panel for multiple journals including the Annals of Internal Medicine, the Journal of Immunology, and Brain Behavior and Immunity. Dr. Fletcher is also a member of the Chronic Fatigue Syndrome Advisory Committee which advises the U.S. Secretary of Health and Human Services.

 

 Return to Our Team

 

2019

Relationship satisfaction, communication self-efficacy, and chronic fatigue syndrome-related fatigue

Milrad SF, Hall DL, Jutagir DR, Lattie EG, Czaja SJ, Perdomo DM, Ironson G, Doss BD, Mendez A, Fletcher MA, Klimas N, Antoni MH. Soc Sci Med. 2019 Sep;237:112392. doi: 10.1016/j.socscimed.2019.112392. Epub 2019 Jul 16.

 

Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant Phenotyping of Women With Chronic Fatigue Syndrome

Morris MC, Cooney KE, Sedghamiz H, Abreu M, Collado F, Balbin EG, Craddock TJA, Klimas NG, Broderick G, Fletcher MA. Clin Ther. 2019 Apr;41(4):656-674.e4. doi: 10.1016/j.clinthera.2019.03.002. Epub 2019 Mar 28.

 

Alterations in DNA Methylation Status Associated with Gulf War Illness

Trivedi MS, Abreu MM, Sarria L, Rose N, Ahmed N, Beljanski V, Fletcher MA, Klimas NG, Nathanson L. DNA Cell Biol. 2019 Jun;38(6):561-571. doi: 10.1089/dna.2018.4469. Epub 2019 Mar 28.

 

Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary

Richman S, Morris MC, Broderick G, Craddock TJA, Klimas NG, Fletcher MA. Clin Ther. 2019 May;41(5):798-805. doi: 10.1016/j.clinthera.2019.02.011. Epub 2019 Mar 11.

 

Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules

Jeffrey MG, Nathanson L, Aenlle K, Barnes ZM, Baig M, Broderick G, Klimas NG, Fletcher MA, Craddock TJA. Clin Ther. 2019 May;41(5):815-835.e6. doi: 10.1016/j.clinthera.2019.01.011. Epub 2019 Mar 6.

 

Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness

Michalovicz LT, Locker AR, Kelly KA, Miller JV, Barnes Z, Fletcher MA, Miller DB, Klimas NG, Morris M, Lasley SM, O'Callaghan JP. Neurotoxicology. 2019 Jan;70:26-32. doi: 10.1016/j.neuro.2018.10.006. Epub 2018 Oct 16.

 

2018

Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns

Trivedi MS, Oltra E, Sarria L, Rose N, Beljanski V, Fletcher MA, Klimas NG, Nathanson L. PLoS One. 2018 Jul 23;13(7):e0201066. doi: 10.1371/journal.pone.0201066. eCollection 2018.

 

Psychoneuroimmunology and Natural Killer Cells: The Chromium-Release Whole-Blood Assay

Fletcher MA, Barnes Z, Broderick G, Klimas NG. Methods Mol Biol. 2018;1781:209-220. doi: 10.1007/978-1-4939-7828-1_12.

 

Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression

Tory Toole J, Rice MA Jr, Craddock TJA, Nierenberg B, Klimas NG, Fletcher MA, Zysman J, Morris M, Broderick G. Methods Mol Biol. 2018;1781:121-144. doi: 10.1007/978-1-4939-7828-1_8.

 

Exploring the Diagnostic Potential of Immune Biomarker Co-expression in Gulf War Illness

Broderick G, Fletcher MA, Gallagher M, Barnes Z, Vernon SD, Klimas NG. Methods Mol Biol. 2018;1781:101-120. doi: 10.1007/978-1-4939-7828-1_7.

 

Increasing Resilience to Traumatic Stress: Understanding the Protective Role of Well-Being

Tory Toole J, Rice MA Jr, Cargill J, Craddock TJA, Nierenberg B, Klimas NG, Fletcher MA, Morris M, Zysman J, Broderick G. Methods Mol Biol. 2018;1781:87-100. doi: 10.1007/978-1-4939-7828-1_6. Review.

 

Associations Among Trajectories of Sleep Disturbance, Depressive Symptomology and 24-Hour Urinary Cortisol in HIV+ Women Following a Stress Management Intervention

McIntosh R, Antoni M, Seay J, Fletcher MA, Ironson G, Klimas N, Kumar M, Schneiderman N. Behav Sleep Med. 2019 Sep-Oct;17(5):605-620. doi: 10.1080/15402002.2018.1435545. Epub 2018 Feb 20.

 

Depression, evening salivary cortisol and inflammation in chronic fatigue syndrome: A psychoneuroendocrinological structural regression model

Milrad SF, Hall DL, Jutagir DR, Lattie EG, Czaja SJ, Perdomo DM, Fletcher MA, Klimas N, Antoni MH. Int J Psychophysiol. 2018 Sep;131:124-130. doi: 10.1016/j.ijpsycho.2017.09.009. Epub 2017 Sep 14.

 

2017

Myalgic encephalomyelitis/chronic fatigue syndrome and gulf war illness patients exhibit increased humoral responses to the herpesviruses-encoded dUTPase: Implications in disease pathophysiology

Halpin P, Williams MV, Klimas NG, Fletcher MA, Barnes Z, Ariza ME. J Med Virol. 2017 Sep;89(9):1636-1645. doi: 10.1002/jmv.24810. Epub 2017 Apr 26.

 

Change in urinary cortisol excretion mediates the effect of angry/hostile mood on 9 month diastolic blood pressure in HIV+ adults

McIntosh RC, Antoni M, Carrico A, Duran R, Hurwitz BE, Ironson G, Fletcher MA, Klimas N, Kumar M, Schneiderman N. J Behav Med. 2017 Aug;40(4):620-630. doi: 10.1007/s10865-017-9827-1. Epub 2017 Feb 2.

 

Psychological Distress Mediates the Effect of Alexithymia on 2-Year Change in HIV Viral Load

McIntosh RC, Ironson G, Antoni M, Lai B, Kumar M, Fletcher MA, Schneiderman N. Int J Behav Med. 2017 Apr;24(2):294-304. doi: 10.1007/s12529-016-9602-7.

 

2016

Poor sleep quality is associated with greater circulating pro-inflammatory cytokines and severity and frequency of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) symptoms in women

Milrad SF, Hall DL, Jutagir DR, Lattie EG, Ironson GH, Wohlgemuth W, Nunez MV, Garcia L, Czaja SJ, Perdomo DM, Fletcher MA, Klimas N, Antoni MH. J Neuroimmunol. 2017 Feb 15;303:43-50. doi: 10.1016/j.jneuroim.2016.12.008. Epub 2016 Dec 14.

Telephone-administered versus live group cognitive behavioral stress management for adults with CFS

Hall DL, Lattie EG, Milrad SF, Czaja S, Fletcher MA, Klimas N, Perdomo D, Antoni MH. J Psychosom Res. 2017 Feb;93:41-47. doi: 10.1016/j.jpsychores.2016.12.004. Epub 2016 Dec 8.

 

Tracking Post-Infectious Fatigue in Clinic using Routine Lab Tests

Harvey, J.M., Broderick, G., Bowie, A., Barnes, Z.M., Katz, B.Z., O'Gorman, M.R., Vernon, S.D., Fletcher, M.A., Klimas, N.G., Taylor, R. BMC Pediatr. 2016 Apr 26;16(1):54. doi: 10.1186/s12887-016-0596-8. PMID:27118537

 

Illness Progression in Chronic Fatigue Syndrome: A Shifting Immune Baseline

Russell, L., Broderick, G., Taylor, R., Fernandes, H., Harvey, J., Barnes, Z., Smylie, A., Collado, F., Balbin, E.G., Katz, B.Z., Klimas, N.G., Fletcher, M.A.. BMC Immunol. 2016 Mar 10;17:3. doi: 10.1186/s12865-016-0142-3. PMID:26965484


Alexithymia, Assertiveness and Psychosocial Functioning in HIV: Implications for Medication Adherence and Disease Severity

McIntosh, R.C., Ironson, G., Antoni, M., Fletcher, M.A., Schneiderman, N. AIDS Behav. 2016 Feb;20(2):325-38. doi: 10.1007/s10461-015-1126-7.PMID:26143246


2015

Achieving Remission in Gulf War Illness: A Simulation-Based Approach to Treatment Design
Craddock, T.J., Del Rosario, R.R., Rice, M., Zysman, J.P., Fletcher, M.A., Klimas, N.G., Broderick, G. PLoS One. 2015 Jul 20;10(7):e0132774. doi:10.1371/journal.pone.0132774. eCollection 2015. PMID:26192591
Using Gene Expression Signatures to Identify Novel Treatment Strategies in Gulf War Illness

Craddock, T.J., Harvey, J.M., Nathanson, L., Barnes, Z.M., Klimas, N.G.,Fletcher, M.A., Broderick, G. BMC Med Genomics. 2015 Jul 9;8:36. doi: 10.1186/s12920-015-0111-3. PMID:26156520


Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper Bound under Constraints Typical of In Vivo Studies

Vashishtha, S., Broderick, G., Craddock, T.J., Fletcher, M.A., Klimas, N.G. PLoS One. 2015 May 18;10(5):e0127364. doi: 10.1371/journal.pone.0127364. eCollection 2015.PMID:25984725


Spiritual Coping Predicts CD4-Cell Preservation and Undetectable Viral Load Over Four Years

Kremer, H., Ironson, G., Kaplan, L., Stuetzele, R., Baker, N., Fletcher, M.A. AIDS Care. 2015;27(1):71-9. doi: 10.1080/09540121.2014.952220. Epub 2014 Oct 8. PMID:25297848

 

Psychosocial and Neurohormonal Predictors of HIV Disease Progression (CD4 Cells and Viral Load): A 4 Year Prospective Study
Ironson, G., O'Cleirigh, C., Kumar, M., Kaplan, L., Balbin, E., Kelsch, C.B., Fletcher, M.A., Schneiderman, N. AIDS Behav. 2015 Aug;19(8):1388-97. doi: 10.1007/s10461-014-0877-x.PMID:25234251
 

2014

Stress Management Skills, Cortisol Awakening Response, and Post-Exertional Malaise in Chronic Fatigue Syndrome
Hall, D.L., Lattie, E.G., Antoni, M.H., Fletcher, M.A., Czaja, S., Perdomo, D., Klimas, N.G. Psychoneuroendocrinology. 2014 Nov;49:26-31. doi: 10.1016/j.psyneuen.2014.06.021. Epub 2014 Jul 6.
Spiritual Coping Predicts CD4-Cell Preservation and Undetectable Viral Load over Four Years

Kremer, H., Ironson, G., Kaplan, L., Stuetzele, R., Baker, N., Fletcher, M.A. AIDS Care. 2014 Oct 8:1-9. 


Psychosocial and Neurohormonal Predictors of HIV Disease Progression (CD4 Cells and Viral Load): A 4 Year Prospective Study

Ironson, G., O'Cleirigh, C., Kumar, M., Kaplan, L., Balbin, E., Kelsch, C.B., Fletcher, M.A., Schneiderman, N. AIDS Behav. 2014 Sep 19.


Taking the Pulse of Aging: Mapping Pulse Pressure and Elasticity in Cerebral Arteries with Optical Methods

Fabiani, M., Low, K.A., Tan, C.H., Zimmerman, B., Fletcher, M.A., Schneider-Garces, N., Maclin, E.L., Chiarelli, A.M., Sutton, B.P., Gratton, G. Psychophysiology. 2014 Aug 6. doi: 10.1111/psyp.12288.


Pneumococcal Empyema and Complicated Pneumonias: Global Trends in Incidence, Prevalence, and Serotype Epidemiology

Fletcher, M.A., Schmitt, H.J., Syrochkina, M., Sylvester, G. Eur J Clin Microbiol Infect Dis. 2014 Jun;33(6):879-910. doi: 10.1007/s10096-014-2062-6. Epub 2014 Feb 23.


Alexithymia is Linked to Neurocognitive, Psychological, Neuroendocrine, and Immune Dysfunction in Persons Living with HIV

McIntosh, R.C., Ironson, G., Antoni, M., Kumar, M., Fletcher, M.A., Schneiderman, N. Brain Behav Immun. 2014 Feb;36:165-75. doi: 10.1016/j.bbi.2013.10.024. Epub 2013 Nov 1.


Oxytocin, Social Support, and Sleep Quality in Low-Income Minority Women Living with HIV

Fekete, E.M., Seay, J., Antoni, M.H., Mendez, A.J., Fletcher, M.A., Szeto, A., Schneiderman, N. Behav Sleep Med. 2014;12(3):207-21. doi: 10.1080/15402002.2013.791297. Epub 2013 Jun 25.


Cardiorespiratory Fitness Mediates the Effects of Aging on Cerebral Blood Flow

Zimmerman, B., Sutton, B.P., Low, K.A., Fletcher, M.A., Tan, C.H., Schneider-Garces, N., Li, Y., Ouyang, C., Maclin, E.L., Gratton, G., Fabiani, M. Front Aging Neurosci. 2014 Apr 7;6:59. doi: 10.3389/fnagi.2014.00059. eCollection 2014.


A Role for Homeostatic Drive in the Perpetuation of Complex Chronic Illness: Gulf War Illness and Chronic Fatigue Syndrome

Craddock, T.J., Fritsch, P., Rice, M.A. Jr., del Rosario, R.M., Miller, D.B., Fletcher, M.A., Klimas, N.G., Broderick, G. PLoS One. 2014 Jan 8;9(1):e84839. doi: 10.1371/journal.pone.0084839. eCollection 2014. Erratum in: PLoS One. 2014;9(4):e94161.

 

2013

Self-Reported Sleep Disturbance is Associated with Lower CD4 Count and 24-h Urinary Dopamine Levels in Ethnic Minority Women Living with HIV

Seay, J.S., McIntosh, R., Fekete, E.M., Fletcher, M.A., Kumar, M., Schneiderman, N., Antoni, M.H. Psychoneuroendocrinology. 2013 Nov;38(11):2647-53. doi: 10.1016/j.psyneuen.2013.06.022. Epub 2013 Jul 10.


A Comparison of Sex-Specific Immune Signatures in Gulf War Illness and Chronic Fatigue Syndrome

Smylie, A.L., Broderick, G., Fernandes, H., Razdan, S., Barnes, Z., Collado, F., Sol, C., Fletcher, M.A., Klimas, N. BMC Immunol. 2013 Jun 25;14:29. doi: 10.1186/1471-2172-14-29.


Stress Management, Depression and Immune Status in Lower Income Racial/Ethnic Minority Women Co-infected with HIV and HPV

Lopez, C.R., Antoni, M.H., Pereira, D., Seay, J., Whitehead, N., Potter, J., O'Sullivan, M., Fletcher, M.A. J Appl Biobehav Res. 2013 Mar 1;18(1):37-57. Epub 2013 Mar 8.


Altered immune pathway activity under exercise challenge in Gulf War Illness: An Exploratory Analysis

Broderick, G., Ben-Hamo, R., Vashishtha, S., Efroni, S., Nathanson, L., Barnes, Z., Fletcher, M.A., Klimas, N. Brain Behav Immun. 2013 Feb;28:159-69. doi: 10.1016/j.bbi.2012.11.007. Epub 2012 Nov 29.


Compassionate Love as a Predictor of Reduced HIV Disease Progression and Transmission Risk

Kremer, H., Ironson, G., Kaplan, L., Stuetzle, R., Fletcher, M.A. Evid Based Complement Alternat Med. 2013;2013:819021. doi: 10.1155/2013/819021. Epub 2013 Nov 18.


Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Symptom Severity: Stress Management Skills are Related to Lower Illness Burden

Lattie, E.G., Antoni, M.H., Fletcher, M.A., Czaja, S., Perdomo, D., Sala, A., Nair, S., Fu, S.H., Penedo, F.J., Klimas, N. Fatigue. 2013;1(4). doi: 10.1080/21641846.2013.843255.

 

2012

Health Locus of Control Beliefs and Healthy Survival with AIDS

Ruffin, R., Ironson, G., Fletcher, M.A., Balbin, E., Schneiderman, N. Int J Behav Med. 2012 Dec;19(4):512-7. doi: 10.1007/s12529-011-9185-2.


Biomarkers for Chronic Fatigue

Klimas, N.G., Broderick, G., Fletcher, M.A. Brain Behav Immun. 2012 Nov;26(8):1202-10. doi: 10.1016/j.bbi.2012.06.006. Epub 2012 Jun 23. Review.


Cytokine Expression Profiles of Immune Imbalance in Post-Mononucleosis Chronic Fatigue

Broderick, G., Katz, B.Z., Fernandes, H., Fletcher, M.A., Klimas, N., Smith, F.A., O'Gorman, M.R., Vernon, S.D., Taylor, R. J Transl Med. 2012 Sep 13;10:191. doi: 10.1186/1479-5876-10-191.


Stress Management Skills, Neuroimmune Processes and Fatigue Levels in Persons with Chronic Fatigue Syndrome

Lattie, E.G., Antoni, M.H., Fletcher, M.A., Penedo, F., Czaja, S., Lopez, C., Perdomo, D., Sala, A., Nair, S., Fu, S.H., Klimas, N. Brain Behav Immun. 2012 Aug;26(6):849-58. doi: 10.1016/j.bbi.2012.02.008. Epub 2012 Mar 6.


Erratum to "Pneumococcal Conjugate Vaccines and Otitis Media: An Appraisal of the Clinical Trials"

Fletcher, M.A., Fritzell, B. Int J Otolaryngol. 2012;2012:590206. Epub 2012 Sep 19.


Pneumococcal Conjugate Vaccines and Otitis Media: An Appraisal of the Clinical Trials

Fletcher, M.A., Fritzell, B. Int J Otolaryngol. 2012;2012:312935. doi: 10.1155/2012/312935. Epub 2012 Jun 3.


Psychoneuroimmunology and Natural Killer Cells: The Chromium Release Whole Blood Assay

Fletcher, M.A., Barnes, Z., Broderick, G., Klimas, N.G. Methods Mol Biol. 2012;934:313-24. doi: 10.1007/978-1-62703-071-7_16.


Exploring the Diagnostic Potential of Immune Biomarker Coexpression in Gulf War Illness

Broderick, G., Fletcher, M.A., Gallagher, M., Barnes, Z., Vernon, S.D., Klimas, N.G. Methods Mol Biol. 2012;934:145-64. doi: 10.1007/978-1-62703-071-7_8.

 

2011

View of God as Benevolent and Forgiving or Punishing and Judgmental Predicts HIV Disease Progression

Ironson, G., Stuetzle, R., Ironson, D., Balbin, E., Kremer, H., George, A., Schneiderman, N., Fletcher, M.A. J Behav Med. 2011 Dec;34(6):414-25. doi: 10.1007/s10865-011-9314-z. Epub 2011 Feb 22.


Stress Buffering Effects of Oxytocin on HIV Status in Low-Income Ethnic Minority Women

Fekete, E.M., Antoni, M.H., Lopez, C., Mendez, A.J., Szeto, A., Fletcher, M.A., Klimas, N., Kumar, M., Schneiderman, N. Psychoneuroendocrinology. 2011 Jul;36(6):881-90. doi: 10.1016/j.psyneuen.2010.12.003. Epub 2011 Jan 6.


A Pilot Study of Cognitive Behavioral Stress Management Effects on Stress, Quality of Life, and Symptoms in Persons with Chronic Fatigue Syndrome

Lopez, C., Antoni, M., Penedo, F., Weiss, D., Cruess, S., Segotas, M.C., Helder, L., Siegel, S., Klimas, N., Fletcher, M.A. J Psychosom Res. 2011 Apr;70(4):328-34. doi: 10.1016/j.jpsychores.2010.11.010. Epub 2011 Jan 15.


Pneumococcal Polysaccharide-Protein CRM197 Conjugate Vaccines, 7- or 9-Valent, in the 2 + 1 Schedule

Fritzell, B., Fletcher, M.A. Expert Rev Vaccines. 2011 Mar;10(3):263-90. doi: 10.1586/erv.11.11.


A Pilot Study of Immune Network Remodeling Under Challenge in Gulf War Illness

Broderick, G., Kreitz, A., Fuite, J., Fletcher, M.A., Vernon, S.D., Klimas, N. Brain Behav Immun. 2011 Feb;25(2):302-13. doi: 10.1016/j.bbi.2010.10.011. Epub 2010 Oct 16.

 

2010

Plasma Neuropeptide Y: A Biomarker for Symptom Severity in Chronic Fatigue Syndrome

Fletcher MA, Rosenthal M, Antoni M, Ironson G, Zeng XR, Barnes Z, Harvey JM, Hurwitz B, Levis S, Broderick G, Klimas NG.Behav Brain Funct. 2010 Dec 29;6:76. doi: 10.1186/1744-9081-6-76.


A Formal Analysis of Cytokine Networks in Chronic Fatigue Syndrome

Broderick, G., Fuite, J., Kreitz, A., Vernon, S.D., Klimas, N., Fletcher, M.A. Brain Behav Immun. 2010 Oct;24(7):1209-17. doi: 10.1016/j.bbi.2010.04.012. Epub 2010 May 4.


A Comparison of Immune Functionality in Viral Versus Non-Viral CFS Subtypes

Porter, N., Lerch, A., Jason, L.A., Sorenson, M., Fletcher, M.A., Herrington, J. J Behav Neurosci Res. 2010 Jun 1;8(2):1-8.


Biomarkers in Chronic Fatigue Syndrome: Evaluation of Natural Killer Cell Function and Dipeptidyl Peptidase IV/CD26

Fletcher, M.A., Zeng, X.R., Maher, K., Levis, S., Hurwitz, B., Antoni, M., Broderick, G., Klimas, N.G. PLoS One. 2010 May 25;5(5):e10817. doi: 10.1371/journal.pone.0010817.

 

2009

Plasma Cytokines in Women with Chronic Fatigue Syndrome

Fletcher, M.A., Zeng, X.R., Barnes, Z., Levis, S., Klimas, N.G. J Transl Med. 2009 Nov 12;7:96. doi: 10.1186/1479-5876-7-96.


Men's Serostatus Disclosure to Parents: Associations Among Social Support, Ethnicity, and Disease Status in Men Living with HIV

Fekete, E.M., Antoni, M.H., Lopez, C.R., Durán, R.E., Penedo, F.J., Bandiera, F.C., Fletcher, M.A., Klimas, N., Kumar, M., Schneiderman, N. Brain Behav Immun. 2009 Jul;23(5):693-9. doi: 10.1016/j.bbi.2009.01.007. Epub 2009 Jan 21.


Impaired Immune Function in Gulf War Illness

Whistler, T., Fletcher, M.A., Lonergan, W., Zeng, X.R., Lin, J.M., Laperriere, A., Vernon, S.D., Klimas, N.G. BMC Med Genomics. 2009 Mar 5;2:12. doi: 10.1186/1755-8794-2-12.


More Severe Pneumococcal Pneumonia in Hospitalized Uruguayan Children

Fletcher, M.A. J Pediatr. 2009 Feb;154(2):307; author reply 307-8. doi: 10.1016/j.jpeds.2008.09.020. No abstract available.


Distress, Sleep Difficulty, and Fatigue in Women Co-Infected with HIV and HPV

Marion, I., Antoni, M., Pereira, D., Wohlgemuth, W., Fletcher, M.A., Simon, T., O'Sullivan, M.J. Behav Sleep Med. 2009;7(3):180-93. doi: 10.1080/15402000902976721.


Depressive Symptoms and Cervical Neoplasia in HIV+ Low-Income Minority Women with Human Papillomavirus Infection

Dodd, S.M., Pereira, D.B., Marion, I., Andrasik, M., Rose, R., Simon, T., Fletcher, M.A., Lucci, J., Maher, K., O'Sullivan, M.J., Efantis-Potter, J., Antoni, M.H. Int J Behav Med. 2009;16(2):181-8. doi: 10.1007/s12529-008-9025-1. Epub 2009 May 8.

 

2008

Vitamin C-Lipid Metabolites: Uptake and Retention and Effect on Plasma C-Reactive Protein and Oxidized LDL Levels in Healthy Volunteers

Pancorbo, D., Vazquez, C., Fletcher, M.A. Med Sci Monit. 2008 Nov;14(11):CR547-51.


Evidence for T-Helper 2 Shift and Association with Illness Parameters in Chronic Fatigue Syndrome (CFS)

Torres-Harding, S., Sorenson, M., Jason, L.A., Maher, K., Fletcher, M.A. Bull IACFS ME. 2008 Fall;16(3):19-33.


Stress Management Effects on Perceived Stress and Cervical Neoplasia in Low-Income HIV-Infected Women

Antoni, M.H., Pereira, D.B., Marion, I., Ennis, N., Andrasik, M.P., Rose, R., McCalla, J., Simon, T., Fletcher, M.A., Lucci, J., Efantis-Potter, J., O'Sullivan, M.J. J Psychosom Res. 2008 Oct;65(4):389-401. doi: 10.1016/j.jpsychores.2008.06.002. Erratum in: J Psychosom Res. 2009 Nov;67(5):463.


Overview of HIV

Klimas, N., Koneru, A.O., Fletcher, M.A. Psychosom Med. 2008 Jun;70(5):523-30. doi: 10.1097/PSY.0b013e31817ae69f. Review.


Written Emotional Disclosure and Processing of Trauma are Associated with Protected Health Status and Immunity in People Living with HIV/AIDS

O'Cleirigh, C., Ironson, G., Fletcher, M.A., Schneiderman, N. Br J Health Psychol. 2008 Feb;13(Pt 1):81-4. doi: 10.1348/135910707X250884.


Perceived Stress and Norepinephrine Predict the Effectiveness of Response to Protease Inhibitors in HIV

Ironson, G., Balbin, E., Stieren, E., Detz, K., Fletcher, M.A., Schneiderman, N., Kumar, M. Int J Behav Med. 2008;15(3):221-6. doi: 10.1080/10705500802219606.


The Associations between Basal Salivary Cortisol and Illness Symptomatology in Chronic Fatigue Syndrome

Torres-Harding, S., Sorenson, M., Jason, L., Maher, K., Fletcher, M.A., Reynolds, N., Brown, M. J Appl Biobehav Res. 2008 Jan 1;13:157-180.

2007

Burden of Paediatric Invasive Pneumococcal Disease in Europe, 2005

McIntosh, E.D., Fritzell, B., Fletcher, M.A. Epidemiol Infect. 2007 May;135(4):644-56. Epub 2006 Sep 7.


Reduction in Pediatric Invasive Pneumococcal Disease in the Basque Country and Navarre, Spain, After Introduction of the Heptavalent Pneumococcal Conjugate Vaccine

Aristegui, J., Bernaola, E., Pocheville, I., García, C., Arranz, L., Durán, G., Pérez, L., Bastida, M., Canduela, C., Herranz Aguirre, M., Garrote, E., Fletcher, M.A., Pérez, C. Eur J Clin Microbiol Infect Dis. 2007 May;26(5):303-10.


Indirect Effects Associated with Widespread Vaccination of Infants with Heptavalent Pneumococcal Conjugate Vaccine (PCV7; Prevnar)

Isaacman, D.J., Fletcher, M.A., Fritzell, B., Ciuryla, V., Schranz, J. Vaccine. 2007 Mar 22;25(13):2420-7. Epub 2006 Sep 18.


Brief Review of the Clinical Effectiveness of PREVENAR Against Otitis Media

Fletcher, M.A., Fritzell, B. Vaccine. 2007 Mar 22;25(13):2507-12. Epub 2006 Sep 20. Review.

 

2006

An Increase in Religiousness/Spirituality Occurs After HIV Diagnosis and Predicts Slower Disease Progression over 4 Years in People with HIV

Ironson, G., Stuetzle, R., Fletcher, M.A. J Gen Intern Med. 2006 Dec;21 Suppl 5:S62-8.


Social Support Mediates Loneliness and Human Herpesvirus Type 6 (HHV-6) Antibody Titers

Dixon, D., Cruess, S., Kilbourn, K., Klimas, N., Fletcher, M.A., Ironson, G., Baum, A., Schneiderman, N., Antoni, M.H. J Appl Soc Psychol. 2006 Jul 31;31(6):1111-1132.


Impaired Natural Immunity, Cognitive Dysfunction, and Physical Symptoms in Patients with Chronic Fatigue Syndrome: Preliminary Evidence for a Subgroup

Siegel, S.D., Antoni, M.H., Fletcher, M.A., Maher, K., Segota, M.C., Klimas, N. J Psychosom Res. 2006 Jun;60(6):559-66.


Reductions in Depressed Mood and Denial Coping During Cognitive Behavioral Stress Management with HIV-Positive Gay Men Treated with HAART

Carrico, A.W., Antoni, M.H., Duran, R.E., Ironson, G., Penedo, F., Fletcher, M.A., Klimas, N., Schneiderman, N. Ann Behav Med. 2006 Apr;31(2):155-64.


Controlling Invasive Pneumococcal Disease: Is Vaccination of At-Risk Groups Sufficient?

Fletcher, M.A., Laufer, D.S., McIntosh, E.D., Cimino, C., Malinoski, F.J. Int J Clin Pract. 2006 Apr;60(4):450-6. Review.


Anger Suppression Mediates the Relationship between Optimism and Natural Killer Cell Cytotoxicity in Men Treated for Localized Prostate Cancer

Penedo, F.J., Dahn, J.R., Kinsinger, D., Antoni, M.H., Molton, I., Gonzalez, J.S., Fletcher, M.A., Roos, B., Carver, C.S., Schneiderman, N. J Psychosom Res. 2006 Apr;60(4):423-7.


Randomized Clinical Trial of Cognitive Behavioral Stress Management on Human Immunodeficiency Virus Viral Load in Gay Men Treated with Highly Active Antiretroviral Therapy

Antoni, M.H., Carrico, A.W., Durán, R.E., Spitzer, S., Penedo, F., Ironson, G., Fletcher, M.A., Klimas, N., Schneiderman, N. Psychosom Med. 2006 Jan-Feb;68(1):143-51.

 

2005

Chronic Fatigue Syndrome is Associated with Diminished Intracellular Perforin

Maher, K.J., Klimas, N.G., Fletcher, M.A. Clin Exp Immunol. 2005 Dec;142(3):505-11.


Psychosocial Factors Predict CD4 and Viral Load Change in Men and Women with Human Immunodeficiency Virus in the Era of Highly Active Antiretroviral Treatment

Ironson, G., O'Cleirigh, C., Fletcher, M.A., Laurenceau, J.P., Balbin, E., Klimas, N., Schneiderman, N., Solomon, G. Psychosom Med. 2005 Nov-Dec;67(6):1013-21.


Sympathoimmune Anomalies Underlying the Response to Stressful Challenge in Human Immunodeficiency Virus Spectrum Disease

Hurwitz, B.E., Brownley, K.A., Motivala, S.J., Milanovich, J.R., Kibler, J.L., Fillion, L., LeBlanc, W.G., Kumar, M., Klimas, N.G., Fletcher, M.A., Schneiderman, N. Psychosom Med. 2005 Sep-Oct;67(5):798-806.


Interleukin-6 and Platelet Protagonists in T Lymphocyte and Virological Response

Miguez, M.J., Rodríguez, A., Hadrigan, S., Asthana, D., Burbano, X., Fletcher, M.A. Platelets. 2005 Aug;16(5):281-6.


Natural Killer Cells and Lymphocytes Increase in Women with Breast Cancer following Massage Therapy

Hernandez-Reif, M., Field, T., Ironson, G., Beutler, J., Vera, Y., Hurley, J., Fletcher, M.A., Schanberg, S., Kuhn, C., Fraser, M. Int J Neurosci. 2005 Apr;115(4):495-510.


Evaluation of the Safety and Immunogenicity of Pneumococcal Seven-Valent Conjugate Vaccine (Prevenar) Administered in Previously Unvaccinated Spanish Children Aged 24 to 36 Months

de Arístegui Fernández, J., Cos Arregui, B., Zurimendi Carril, A., Alday Esteban, M.V., Alzua Ruiz, J., De la Fuente Jausoro, E., Maturana San Pedro, I., López Michelena, M.J., Mourelo Carballo, C., Quintanilla Sánchez, M.I., Abad Therón, I., Cimino, C.O., Fletcher, M.A., Pérez Domínguez, A.Vaccine. 2005 Mar 14;23(16):1917-22.


Cognitive Behavioral Stress Management Effects on Mood, Social Support, and a Marker of Antiviral Immunity are Maintained up to 1 Year in HIV-Infected Gay Men

Carrico, A.W., Antoni, M.H., Pereira, D.B., Fletcher, M.A., Klimas, N., Lechner, S.C., Schneiderman, N. Int J Behav Med. 2005;12(4):218-26.


Dispositional Optimism and the Mechanisms by which it Predicts Slower Disease Progression in HIV: Proactive Behavior, Avoidant Coping, and Depression

Ironson, G., Balbin, E., Stuetzle, R., Fletcher, M.A., O'Cleirigh, C., Laurenceau, J.P., Schneiderman, N., Solomon, G. Int J Behav Med. 2005;12(2):86-97.


Increases in a Marker of Immune System Reconstitution are Predated by Decreases in 24-h Urinary Cortisol Output and Depressed Mood during a 10-Week Stress Management Intervention in Symptomatic HIV-Infected Men

Antoni, M.H., Cruess, D.G., Klimas, N., Carrico, A.W., Maher, K., Cruess, S., Lechner, S.C., Kumar, M., Lutgendorf, S., Ironson, G., Fletcher, M.A., Schneiderman, N. J Psychosom Res. 2005 Jan;58(1):3-13.

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