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E.M. Papper Laboratory of Clinical Immunology

The E. M. Papper Laboratory of Clinical Immunology, directed by Dr. Mary Ann Fletcher, has been associated with research and clinical care for over 30 years. With laboratory facilities at the Davie Campus of NSU and the Miami VA Medical Center, our labs are licensed clinical reference labs in the State of Florida, CLIA certified and NIH, VA and DoD funded research facilities. Current tests performed in the lab include Flow Cytometry, Natural Killer Cell Toxicity, Multiplex Cytokines and EBV viral load assays. Gene expression research and testing is also performed in the laboratory with the use of the NanoString Analyser.

In addition, the laboratory is an established biobank with emergency back-up freezers and is a long standing participant in the ACTG/Duke proficiency testing program for cryopreservation, storage and shipping of peripheral blood mononuclear cells.

The E.M. Papper Laboratory of Clinical Immunology is an independent laboratory. Physicians may send samples to the lab for testing.

Please email EMPapper@nova.edu for a comprehensive list of lab services offered, pricing inquiries, procedure and general questions.

TEST Description CPT

Immunoglobulin Quantitation

 IgG, IgA, IgM 82784 (x3)

Immunoglobulin Subclasses

 IgG1, IgG2, IgG3, IgG4 82787 (x4)

Epstein-Barr Nuclear Antigen (EBNA)

 IgG 86664

Epstein-Barr Virus Early Antigen (EB-EA)

 IgG 86663

Epstein-Barr Virus (VCA)

 IgG 86665

Epstein-Barr Virus (VCA)

 IgM 86665

Herpes Simplex Virus-2

 IgG 86696

Human Herpes Virus-6

 IgG 86790 (x4)

C-Reactive Protein

 86140

Mulitplex 18 Cytokines Panel

 IL-1a, IL-1b IL-4, IL-8, IL-13, IL-23, IL-5, IL-10, IL-15, IL-2, IL-6, IL-12, IL-17, Tumor Necrosis Factor α, Tumor Necrosis Factor β, Interferon Gamma (IFNy), TNF Receptor I, TNF Receptor II 83520 (x18)

In vitro Cytokine Induction Assay, Multiplex 18

 IL-1a, IL-1b IL-4, IL-8, IL-13, IL-23, IL-5, IL-10, IL-15, IL-2, IL-6, IL-12, IL-17, Tumor Necrosis Factor α, Tumor Necrosis Factor β, Interferon Gamma (IFNy), TNF Receptor I, TNF Receptor II 86353 (x2); 83520 (x18)

Lymphocyte Activations/Differential

 CD45, CD3, CD4, CD8, CD5, CD2, CD45RA, CD26, CD56, CD38, CD19, CD95, CD25, CD28, CD14, CD62L, CD11a, CD11b 88184; 88185 (x17)

ComprehensiveLymphocyte Activations/Differential & Natural Killer Cell Cytotoxicity

 CD45, CD3, CD4, CD8, CD5, CD2, CD45RA, CD26, CD56, CD38, CD19, CD95, CD25, CD28, CD14, CD62L, CD11a, CD11b, Lymphocyte Culture 88184; 88185 (x17); 86353 (x4)

T-Cells and T-Cell Subsets

 CD45, CD3, CD4, CD8 88184; 88185 (x3)

T-Cell Subsets and NK-Cells

 CD45, CD3, CD4, CD8, CD14, CD56 88184; 88185 (x5)

T-Cell Subsets and Natural Killer Cell Cytotoxicity

 CD45, CD3, CD4, CD8, CD14, CD56, Lymphocyte Culture 88184; 88185 (x5); 86353 (x4)

T-Cell Subsets and B-Cells

 CD45, CD3, CD4, CD8, CD14, CD19 88184; 88185(x5)

T-Cell Subsets, B-Cells and NK Cells

 CD45, CD3, CD4, CD8, CD14, CD19, CD56 88184; 88185(x6)

Comprehensive T-Cell Subsets, B-Cells and Natural Killer Cell Cytotoxicity

 CD45, CD3, CD4, CD8, CD14, CD19, CD56, Lymphocyte Culture 88184; 88185(x6); 86353(x4)

Neutrophil Oxidative Burst by Flow cytometry; culture

 Flow Cytometry, Culture 88184; 88185; 86353

Leukocyte Adhesion Deficiency; culture

 Flow Cytometry, Culture 88184; 88185; 86353

Perforin and granzymes in NK cells and T cells by flow cytometry and culture

 88184; 88185 (x5)

Comprehensive Natural Killer Cell Cytotoxicity 

 CD3, CD45, CD14, CD56, Lymphocyte Culture 86353 (x4); 88184; 88185(x2); 86357

Complete Blood Count (CBC)

 85025

Erythrocyte Sedimentation Rate (ESR)

 85651

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